Join for Exclusive Member Savings!
Join for Exclusive Member Savings!
American Cruise Line cruise deals open the door to explore American's beautiful and iconic Rivers. American Cruise Line offers cruises on the Mississippi River, the Hudson River and the Columbia and Snake Rivers. Immerse yourself in the southern history and culture of the Mississippi from St. Paul to New Orleans. The stunning views and historical sites of the Hudson River are highlighted on a Hudson River Cruise. The Columbia & Snake river lets you explore the Pacific Northwest. Book now and get the best deals on your next American Cruise Line cruise vacation.
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COLUMBIA & SNAKE RIVER CRUISE
American Pride
Clarkston to Portland/Oregon
Jul 13 - Nov 2, 2026
Fr $5,094
American Pride
Portland/Oregon to Clarkston
Aug 31, 2025 - Nov 9, 2026
Fr $5,094
COLUMBIA & SNAKE RIVER CRUISE
American West
Clarkston to Portland/Oregon
Aug 31 - Oct 12, 2025
Fr $5,500
American West
Clarkston to Portland/Oregon
Aug 31, 2025 - Jul 20, 2026
Fr $5,500
COLUMBIA & SNAKE RIVER CRUISE
American Song
Clarkston to Portland/Oregon
Aug 26, 2025 - Nov 4, 2026
Fr $5,891
COLUMBIA & SNAKE RIVER CRUISE
American Harmony
Clarkston to Portland/Oregon
Sep 5, 2025 - Oct 17, 2026
Fr $6,153
Fall Foliage Cruise
American Glory
New York City to Albany
Sep 30 & Oct 14, 2025
Fr $6,257
Fall Foliage Cruise
American Glory
New York City to Albany
Oct 5 & 19, 2026
Fr $7,000
American Glory
Albany to New York City
Oct 12 & 26, 2026
Fr $7,000
American Glory
Albany to New York City
Oct 7 & 21, 2025
Fr $7,846
Mississippi River Cruise
American Heritage
Roundtrip New Orleans
Mar 29 - May 28, 2026
Fr $3,619
Mississippi River Cruise
American Splendor
Memphis to New Orleans
Oct 28, 2025 - Nov 11, 2026
Fr $4,866
Mississippi River Cruise
American Splendor
New Orleans to Memphis
Aug 26, 2025 - Jun 3, 2026
Fr $4,866
Mississippi River Cruise
American Serenade
Memphis to New Orleans
Oct 24, 2025 - Oct 23, 2026
Fr $5,139
Mississippi River Cruise
American Symphony
New Orleans to Memphis
Mar 4 - Dec 24, 2026
Fr $5,223
American Glory
New York City to Boston
May 22, 2027
Fr $5,693
American Glory
Roundtrip Boston
May 18 - Sep 21, 2026
Fr $5,693
American Glory
Boston to New York City
Sep 28, 2026
Fr $7,000
American Pioneer
New York City to Boston
Apr 16 & 30, 2026
Fr $7,703
American Patriot
Roundtrip Boston
Jun 7 - Aug 26, 2026
Fr $10,564
American Liberty
Charleston/South Carolina to Amelia Island
Feb 21 - May 16, 2026
Fr $6,465
American Eagle
Amelia Island to Charleston/South Carolina
Dec 5, 2025 - Apr 30, 2026
Fr $6,510
American Eagle
Amelia Island to Washington, D.C.
May 13, 2026
Fr $10,480
American Constellation
Roundtrip Juneau
Aug 25, 2025 - Sep 7, 2026
Fr $6,163
American Constitution
Roundtrip Juneau
May 23 - Aug 10, 2026
Fr $6,440
American Constitution
Roundtrip Juneau
Aug 28, 2025 - Aug 27, 2026
Fr $8,876
American Constellation
Seattle to Juneau
May 11, 2026
Fr $9,108
American Constellation
Juneau to Seattle
Sep 15, 2026
Fr $10,514
American Constitution
Juneau to Seattle
Sep 7, 2025 & Sep 6, 2026
Fr $10,514
American Constellation
Fairbanks to Juneau
Aug 26, 2025
Fr $13,959
Upper Mississippi River Cruise
American Melody
Saint Louis to Saint Paul
Aug 29, 2025 - Oct 10, 2026
Fr $5,490
Upper Mississippi River Cruise
American Serenade
Saint Louis to Saint Paul
Jul 11 - Aug 8, 2026
Fr $5,490
Upper Mississippi River Cruise
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Saint Louis to Pittsburgh
Jun 20 & Aug 1, 2026
Fr $9,663
American Constitution
Roundtrip Seattle
Sep 21, 2025 - Oct 18, 2026
Fr $4,876
American Constellation
Roundtrip Seattle
Sep 30, 2025 - Oct 20, 2026
Fr $4,876
American Spirit
Roundtrip Seattle
May 9 - Sep 19, 2026
Fr $5,812
All offers are based on select sailings and categories and are subject to availability at time of booking. All rates are per person based on double occupancy.
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