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A South America cruise vacation offers a world of exploration that is as spectacular as it is diverse. As you sail past the dramatic coastline you are greeted with exotic ports of call, modern and energetic cities, diverse cultures and abundant wildlife. Settled by historic explorers, cities like Rio de Janeiro, Buenos Aires, Lima and Santiago showcase the rich history of South America and its many European roots and cultures. On a South America Cruise you can explore these colorful, modern and exciting South American ports, see their historic sights, sample local cuisines and learn about their varied cultures.
South America boasts some of the worlds most famous and breathtaking destination including Peru's mystical Machu Picchu's ancient ruins, Chile's spectacular fjords, Brazil's Iguazu Falls, the stunning Andes Mountains and even the astonishing Antarctica. Only on a cruise to South America can you take in all of these awe inspiring destinations for a memory that will last a lifetime.
The unique wildlife of South America is abundant. Listen to the chatter of monkeys in the Amazon, watch the seals basking on South America's beaches and see some of the world's most majestic penguins, whales and other wildlife. In the Amazon, cruise through the spectacular rainforests, float past native villages, learn about the history and cultures of the many indigenous tribes and discover the many species that make the Amazon ecosystem so incredible.
Over 180 South America cruise itineraries are offered ranging from 5 to 44 days on ships large and small. Call now or book online to receive exclusive rates and special offers on your next South America cruise.
MSC Seaview
Roundtrip Santos
Nov 29, 2025 - Apr 4, 2026
Fr $649
Seven Seas Splendor
Rio de Janeiro to Buenos Aires
Dec 17, 2025
Fr $5,068
Scenic Eclipse
Rio de Janeiro to Buenos Aires
Oct 11, 2025
Fr $10,297
Marina
Buenos Aires to Rio de Janeiro
Jan 10, 2026
Fr $3,730
Seabourn Venture
Belem to Rio de Janeiro
Oct 30, 2025
Fr $6,903
Azamara Quest
San Antonio/Chile to Fuerte Amador
Mar 2, 2026
Fr $2,635
Oosterdam
San Antonio/Chile to Buenos Aires
Dec 4, 2025 & Feb 22, 2026
Fr $1,830
Celebrity Equinox
Roundtrip Buenos Aires
Dec 6, 2025 - Feb 28, 2026
Fr $1,866
Fr $7,135
Queen Anne
Fort Lauderdale to Rio de Janeiro
Jan 22, 2027
Fr $3,806
Viking Jupiter
Valparaiso to Buenos Aires
Dec 16, 2025 - Feb 22, 2026
Fr $8,299
World Navigator
Ushuaia to Buenos Aires
Mar 3, 2026
Fr $20,205
National Geographic Explorer
Roundtrip Puerto Natales
Nov 14, 2025 - Feb 14, 2027
Fr $11,377
SH Vega
Roundtrip Ushuaia
Dec 1, 2025 - Mar 3, 2027
Fr $8,480
World Voyager
Roundtrip Ushuaia
Dec 18, 2025 - Mar 19, 2026
Fr $11,488
Silver Cloud
Roundtrip Puerto Williams
Nov 26, 2025 - Feb 2, 2027
Fr $17,952
Seabourn Venture
Buenos Aires to Ushuaia
Dec 8, 2025 - Feb 28, 2026
Fr $8,036
MS Fridtjof Nansen
Roundtrip Ushuaia
Oct 30, 2025 - Mar 9, 2026
Fr $9,721
Scenic Eclipse
Roundtrip Buenos Aires
Nov 11, 2025 - Feb 13, 2026
Fr $12,821
Viking Polaris
Buenos Aires to Ushuaia
Nov 3, 2025 - Feb 21, 2026
Fr $12,995
Delfin II
Lima to Nauta
Jul 12 - Nov 1, 2025
Fr $10,005
Seabourn Venture
Roundtrip Belem
Oct 12 & 21, 2025
Fr $6,255
AmaMelodia
Cartagena/Colombia to Panama
Jun 11, 2025 - Jan 7, 2026
Fr $5,638
Delfin III
Roundtrip Callao
May 11 - Nov 9, 2025
Fr $5,983
Explora I
Manaus to San Juan
Feb 17, 2027
Fr $6,749
Marina
Rio de Janeiro to Miami
Mar 17, 2026
Fr $5,264
Viking Sea
Roundtrip San Juan
Dec 15, 2026
Fr $9,999
Seven Seas Mariner
Roundtrip Miami
Nov 9, 2026
Fr $11,148
Volendam
Roundtrip Fort Lauderdale
Nov 24, 2025
Fr $4,443
All offers are based on select sailings and categories and are subject to availability at time of booking. All rates are per person based on double occupancy.
Dramatic Landscapes
The spectacular sights that await you on a cruise to South America include the thundering Iguazu Falls, the Straits of Magellan and Cape Horn's stunning glaciers and fjords. Visit the remote Falkland Islands and journey to Ushuaia, located at the End of the World. Some South American cruises can even take you to Antarctica for a true adventure of a lifetime.
Incredible Machu Picchu
Machu Picchu is one of the most beautiful and enigmatic historical sites in the world. Nested high in the Andes Mountains, far above the clouds, Machu Picchu is the ancient capital of the Inca civilization and is a remarkable sight to behold. It has been revered as a sacred and mystical place and is one of UNESCO's World Heritage Sites.
Incredible Wildlife
The wildlife of South America is as diverse as it is spectacular. It is one of the few places in the world where you can see penguin colonies, condors, whales, sea lions and elephant seals living in their natural habitat. A South America cruise is one of the best ways to see these magnificent creatures.
History and Culture
Take a South America cruise and explore its exciting cities and become immerse in their varied cultures. Visit the city of Rio De Janeiro and take in its Portuguese history. Learn to Tango in Buenos Aires and savor the cuisine in its wonderful restaurants. Enjoy the beautiful wine region near Santiago, Chile and get acquainted with the colonial city of Lima.
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